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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEF2A All Species: 29.09
Human Site: Y105 Identified Species: 53.33
UniProt: Q02078 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02078 NP_001124398.1 507 54811 Y105 S P D P D T S Y V L T P H T E
Chimpanzee Pan troglodytes XP_001139086 503 54307 Y105 S P D P D T S Y V L T P H T E
Rhesus Macaque Macaca mulatta XP_001102710 505 54549 Y105 S P D P D T S Y V L T P H T E
Dog Lupus familis XP_858038 490 52717 Y104 T P H T E E K Y K K I N E E F
Cat Felis silvestris
Mouse Mus musculus Q60929 498 53560 F105 S P D A D D Y F E H S P L S E
Rat Rattus norvegicus Q2MJT0 495 53235 Y105 S P D P D T S Y V L T P H T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507578 507 54968 Y105 S P D P D T S Y V L T P H T E
Chicken Gallus gallus Q9W6U8 499 53650 F105 S P D A D D Y F E H S P L S E
Frog Xenopus laevis Q03414 516 56328 Y144 S P D P D G S Y V L T P H T E
Zebra Danio Brachydanio rerio NP_571376 460 49093 K91 I V E K L R N K G H N D C P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40791 539 57097 Y105 S P E A E T D Y T L T P R T E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38847 268 30310
Baker's Yeast Sacchar. cerevisiae Q12224 676 73465 S231 N L N Q P S S S S S S P S T M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 98.4 94.6 N.A. 89.7 93.6 N.A. 93 83.2 79.2 70.6 N.A. 31.3 N.A. N.A. N.A.
Protein Similarity: 100 99.2 98.8 95.4 N.A. 92.9 95.4 N.A. 95.4 89.7 85.2 78.3 N.A. 46 N.A. N.A. N.A.
P-Site Identity: 100 100 100 13.3 N.A. 40 100 N.A. 100 40 93.3 0 N.A. 60 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 26.6 N.A. 60 100 N.A. 100 60 93.3 13.3 N.A. 73.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.2 21.8 N.A.
Protein Similarity: N.A. N.A. N.A. 36.2 36.6 N.A.
P-Site Identity: N.A. N.A. N.A. 0 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 24 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 62 0 62 16 8 0 0 0 0 8 0 0 0 % D
% Glu: 0 0 16 0 16 8 0 0 16 0 0 0 8 8 70 % E
% Phe: 0 0 0 0 0 0 0 16 0 0 0 0 0 0 8 % F
% Gly: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % G
% His: 0 0 8 0 0 0 0 0 0 24 0 0 47 0 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 0 0 0 8 0 0 8 8 8 8 0 0 0 0 0 % K
% Leu: 0 8 0 0 8 0 0 0 0 54 0 0 16 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 8 0 8 0 0 0 8 0 0 0 8 8 0 0 0 % N
% Pro: 0 77 0 47 8 0 0 0 0 0 0 77 0 8 0 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % R
% Ser: 70 0 0 0 0 8 54 8 8 8 24 0 8 16 8 % S
% Thr: 8 0 0 8 0 47 0 0 8 0 54 0 0 62 0 % T
% Val: 0 8 0 0 0 0 0 0 47 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 16 62 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _